Wednesday Afternoon Lecture Series
The Annual Florence Mahoney Lecture
Aging is a crucial risk factor in a constellation of human diseases, including cancer and neurodegeneration. Along with other risk factors such as environmental exposures, diet, behavior and heredity, these risks can be understood through their impact on the epigenetic landscape in ways that ultimately lead to the burden of disease. Among these risks, aging had been regarded as fixed, but current thinking holds that aging is plastic and its pace can be slowed or even reversed. Dr. Berger’s laboratory has been studying the causal roles of epigenetics in aging, focused on structural features of chromatin and gene regulation in relation to senescence. These studies of the epigenetic landscape of senescent cells reveal profound alterations both in genome-wide transcription and histone post-translational modifications (which help regulate the structure of chromatin). Most of the epigenetic changes cover broad domains of the genome, and the locations and underlying gene regulatory changes indicate that, on one hand, oncogenic escape results from induction of specific genes that regulate pluripotency, while on the other hand aging-related alterations are caused by mutations that accumulate over “open domains” in chromatin after many cell replications. These findings provide a broad view of the relationship between aging and disease. Further, the chromatin changes lead to profound implications for potential epigenetic therapeutics to address diseases of aging.
For more information go to http://wals.od.nih.gov
Air date: 3/12/2014 3:00:00 PM
Neuroscience Seminar Series
Air date: 3/17/2014 12:00:00 PM
The National Center for Complementary and Alternative Medicine (NCCAM) presents the Integrative Medicine Research Lecture series. The series provides overviews of the current state of research and practice involving complementary health therapies, and explores perspectives on the emerging discipline of integrative medicine. Richard A. Deyo, M.D., M.P.H, is the Kaiser Permanente Professor of Evidenced-Based Family Medicine in the Department of Family Medicine at Oregon Health and Science University. Dr. Deyo will discuss the results of his research, which suggest that complementary health approaches, such as spinal manipulation, acupuncture, and massage, have benefits at least equal to conventional care for back pain, but perhaps with different mechanisms and for different patients. For more information go to: http://nccam.nih.gov/news/events/IMlectures
For more information go to http://nccam.nih.gov/news/events/IMlectures
Air date: 4/14/2014 10:00:00 AM
The Office of AIDS Research Advisory Council (OARAC) will address NIH AIDS research priorities. An update will be provided on the lastest changes made to the federal treatment and prevention guidelines by the OARAC Working Groups responsible for the guidelines.
Air date: 4/10/2014 8:30:00 AM
The NIH Symposium on Advanced Networking for Data-Intensive Biomedical Research will discuss with and educate staff on the issues associated with data-intensive biomedical research with a focus on advanced networking and data movement. The symposium will include data intensive science presentations, Infrastructure+ discussions, and related technical discussions. The focus will be on specific use cases, their challenges, and their solutions.
For more information go to https://respond.niaid.nih.gov/conferences/bioinformatics2014/Pages/default.aspx
Air date: 4/9/2014 9:00:00 AM
The U.S. Office of Personnel Management (OPM) authorized agencies to grant dual compensation (salary offset) waivers for certain reemployed annuitants as provided under the National Defense Authorization Act for Fiscal Year 2010. The waiver is suitable for workforce retention of retirees with unique technical skills or those with capabilities to serve as mentors to IC staff. The NIH authority to appoint under this Act is for situations when the agency needs to retain the services of a particular individual based on his/her expertise, which meets one of the following critical needs of the agency:
- Functions critical to the NIH mission;
- Implementation or oversight of the American Recovery and
Reinvestment Act of 2009 or the Troubled Asset Relief Program;
- Development, management, or oversight of agency procurement actions;
- Promotion of training or mentoring of employees;
- Recruitment and retention of employees; or
- Responding to an emergency involving a direct threat to life or property or other unusual circumstances.
Reemployed annuitants using this flexibility can work part-time and received salary and their full annuity.
For more information go to http://oeodm.od.nih.gov/edi-week.htm
Air date: 3/25/2014 9:00:00 AM
Bullying is defined as intimidating or harassing behavior such as threats or other conduct which, in any way, creates a hostile environment; impairs agency operations; or frightens, alarms, or inhibits others. Psychological intimidation or harassment includes making statements which are false, malicious, disparaging, derogatory, rude, disrespectful, abusive, obnoxious, insubordinate, or which have the intent to hurt others’ reputations. Physical intimidation or harassment may include holding, impeding or blocking movement, following, stalking, touching or any other inappropriate physical contact or advances. This course seeks to help employees understand the circumstances that can trigger violence in the workplace and to offer strategies for preventing the escalation of conflict.
For more information go to http://oeodm.od.nih.gov/edi-week.htm
Air date: 3/25/2014 1:00:00 PM
The primary goal of the festival is to explore the open science movement through presentations on open access, open systems/software, and open data. As the government strives for transparency and engagement, the NIH also seeks to enhance reproducibility in research. The open science movement holds that transparent science is better science. By sharing data early on, rather than post-publication, researchers have a huge opportunity for collaborative models of discovery. The festival will feature presentations by subject matter experts from government agencies, academia, and non-profit organizations.
Air date: 4/8/2014 9:00:00 AM
This is the third meeting of the 2015 Dietary Guidelines Advisory Committee (DGAC). The DGAC will develop an advisory report for the Secretaries of Health and Human Services and of Agriculture. This Committee’s advisory report will provide the scientific basis for the 2015 Dietary Guidelines for Americans policy document developed by the Federal government.
Air date: 3/14/2014 8:00:00 AM
The 2nd Annual Office of Human Resources Awards Ceremony will celebrate some of the successes of the NIH HR workforce. Recipients will be recognized in a number of categories for their outstanding contributions to the NIH mission.
Air date: 3/25/2014 10:00:00 AM